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Wednesday, April 25, 2012
Pegatron Corp. Signs Patent Agreement With Microsoft Over Android, Chrome OS Devices
Tuesday, April 24, 2012
New technique may help severely damaged nerves regrow and restore function
ScienceDaily (Apr. 22, 2012) ? Engineers at the University of Sheffield have developed a method of assisting nerves damaged by traumatic accidents to repair naturally, which could improve the chances of restoring sensation and movement in injured limbs.
In a collaborative study with Laser Zentrum Hannover (Germany) published April 23, 2012 in the journal Biofabrication, the team describes a new method for making medical devices called nerve guidance conduits or NGCs.
The method is based on laser direct writing, which enables the fabrication of complex structures from computer files via the use of CAD/CAM (computer aided design/manufacturing), and has allowed the research team to manufacture NGCs with designs that are far more advanced than previously possible.
Currently patients with severe traumatic nerve damage suffer a devastating loss of sensation and/or movement in the affected limb. The traditional course of action, where possible, is to surgically suture or graft the nerve endings together. However, reconstructive surgery often does not result in complete recovery.
"When nerves in the arms or legs are injured they have the ability to re-grow, unlike in the spinal cord; however, they need assistance to do this," said University of Sheffield Professor of Bioengineering, John Haycock. "We are designing scaffold implants that can bridge an injury site and provide a range of physical and chemical cues for stimulating this regrowth."
The new conduit is made from a biodegradable synthetic polymer material based on polylactic acid and has been designed to guide damaged nerves to re-grow through a number of small channels.
"Nerves aren't just like one long cable, they're made up of lots of small cables, similar to how an electrical wire is constructed," said lead author Dr Frederik Claeyssens, of the University's Department of Materials Science and Engineering. "Using our new technique we can make a conduit with individual strands so the nerve fibres can form a similar structure to an undamaged nerve."
Once the nerve is fully regrown, the conduit biodegrades naturally. The team hopes that this approach will significantly increase recovery for a wide range of peripheral nerve injuries.
In laboratory experiments, nerve cells added to the polymer conduit grew naturally within its channelled structure and the research team is now working towards clinical trials.
"If successful we anticipate these scaffolds will not just be applicable to peripheral nerve injury, but could also be developed for other types of nerve damage too. The technique of laser direct writing may ultimately allow production of scaffolds that could help in the treatment of spinal cord injury" said Dr Claeyssens.
"What's exciting about this work is that not only have we designed a new method for making nerve guide scaffolds which support nerve growth, we?ve also developed a method of easily reproducing them through micromolding.
"This technology could make a huge difference to patients suffering severe nerve damage," he added.
This research was funded by the Engineering and Physical Sciences Research Council.
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The above story is reprinted from materials provided by University of Sheffield.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- A Koroleva, A A Gill, I Ortega, J W Haycock, S Schlie, S D Gittard, B N Chichkov, F Claeyssens. Two-photon polymerization-generated and micromolding-replicated 3D scaffolds for peripheral neural tissue engineering applications. Biofabrication, 2012; 4 (2): 025005 DOI: 10.1088/1758-5082/4/2/025005
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
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Monday, April 23, 2012
The Single Best Way to Avoid Getting Screwed on Craigslist [Craigslist]
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HP LaserJet Pro 400 Color MFP M475dn
The HP LaserJet Pro 400 Color MFP M475dn ($699 direct) has an awkward name, and nobody is going to give it any awards for speed. But it has a good feature set and above-average output; it?s especially strong in graphics. This makes it a very respectable choice as a color laser multifunction printer (MFP) for a smaller office.
The M475dn prints, copies, faxes, and scans; it can fax either from its 3.5-inch color touch screen or from a computer (PC Fax). You can scan to a USB thumb drive, email, or a network folder. It has a 50-sheet automatic document feeder (ADF) for faxing, scanning, or copying multi-page documents without you having to feed each page by hand. It can scan at up to legal size using the ADF.
This MFP measures 19.7 by 16.5 by 19.0 inches (HWD) and weighs 65 pounds, too big to share a desk with, and moving it into place is a 2-person job. The M475dn has a 300-sheet standard paper capacity, split between a 250-sheet input tray and 50-sheet multipurpose tray; a second 250-sheet tray is available as an option ($137 direct). It has an automatic duplexer for printing on both sides of a sheet of paper, which can save you a lot of paper.
The M475dn is capable of running HP?s Web apps and comes with a generous selection of them pre-installed. Their printable content ranges from forms to news feeds, coloring book pages, Sudoku puzzles, and more. The M475dn is also ePrint enabled; HP assigns an e-mail address to the printer (which you can later customize), you can send documents to that address, and the printer will automatically print them out (as long as it?s connected to the Internet).
The M475dn offers USB and Ethernet connectivity. (An otherwise identical WiFi-enabled version of the printer, the M475dw, is available for $749 direct.) I tested it over the Ethernet connection with a PC running Windows Vista.
Print Speed
I timed the M475dn on the latest version of our business applications suite (using QualityLogic's hardware and software for timing), at a rather sluggish 3.2 effective pages per minute (ppm), even considering its relatively low rated print speed of 21 ppm?which should be about the speed you would get if you were to print text only. The Editors? Choice Dell 2155cn ($549.99 direct) finished the same tests at a much faster 5.9 ppm clip, while the OKI MC561 ($750 street) was even faster, at 7.2 ppm.
Print Quality
Overall output quality for the M475dn was slightly above average, thanks to very good graphics quality. Text was slightly below average for a laser, which still translates to very good?fine for any business use except those requiring very small fonts, like some desktop publishing applications, or documents like resumes that need to make a good visual impression.
Graphics were of good enough quality that I wouldn?t hesitate to hand them to clients I was seeking to impress, or?for that matter?use for marketing materials. The only issues I encountered were minor, some blotchiness in a couple of color backgrounds due to uneven toner distribution and some mild posterization.
Photo quality was a little on the high side of average. Photos generally showed very good color, although a couple of them had modest tints. Several showed dithering, and there was a loss of detail in several bright areas.
The Editors? Choice Dell 2155cn is considerably faster than the M475dn, and has slightly better overall output quality and a lower price tag. It lacks an auto-duplexer, and although they both have 250-sheet main trays, the Dell 2155cn?s multipurpose feeder is limited to a single sheet. The OKI MC561has blazing speed and even has a duplexing ADF, letting you copy, fax, and scan 2-sided documents. Its output quality isn?t up to either the HP or the Dell 2155cn, however. The OKI MC561has slightly lower color costs that the other two.
Unless print speed is a strong consideration, the HP LaserJet Pro 400 Color MFP M475dn is a good choice as a color laser MFP to anchor a small office. It has a very solid feature set, including HP Web apps and ePrint capabilities, and good output quality highlighted by beautiful graphics.
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??? HP LaserJet Pro 400 Color MFP M475dn
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